Posted: November 15th, 2022

Write a paper covering the various aspects of an your infectious disease of choice in accordance to the topics listed below. • Taxonomic classification • History and interesting facts • Notable outbreaks • Morphological and growth characteristics • Disease geography • Rout of transmission / Life cycle • Mechanisms of pathogenesis • Diagnosis / symptoms • Treatment modalities / availability of vaccine • Public health initiatives / preventative actions • References

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Microbiology Final paper
Infectious diseases have killed more people than any other single cause, and have remained the primary source of morbidity and mortality worldwide. Infectious diseases are disorders caused by microorganisms — such as bacteria, viruses, fungi or parasites. Many of these organisms are part of our bodies’ microflora, and are generally beneficial, but under certain circumstances they may lead to disease. Furthermore, other infectious diseases can be transmitted directly or indirectly: from one person to another, from insects or animals, or can be acquired by ingestion of contaminated foods and water, as well as by environmental exposure. Accordingly, our ever growing world population is facing new challenges such as emerging and re-emerging infectious disease associated with globalization and increased populations of immunocompromised individuals. Therefore, the prescription and/or administration of an antimicrobial and the potential emergence of resistance among pathogenic microbial isolates requires a working knowledge of the diversity of infectious agents, testing and profiling techniques used to identify them, treatment modalities and preventative actions. Accordingly, the objectives of the following term paper is to acquaint students with performing original literature research pertaining to various aspects of a particular infectious agent, ranging from its history and discovery to morphology and growth characteristics to mechanisms of pathogenicity and the availability of treatment or preventative options, and lastly public health related management strategies or policies.
To that end, each student will be select an infectious agent of their interest at the beginning of the quarter, and research their chosen infectious agents outside of class using textbooks, web resources, and current literature. You will be expected to prepare a, six to eight page, written paper covering the various aspects of an your infectious disease of choice in accordance to the topics listed below.
• Taxonomic classification
• History and interesting facts
• Notable outbreaks
• Morphological and growth characteristics
• Disease geography
• Rout of transmission / Life cycle
• Mechanisms of pathogenesis
• Diagnosis / symptoms
• Treatment modalities / availability of vaccine
• Public health initiatives / preventative actions
• References
The final, submitted, paper must include the above mentioned topics organized into sections with headings. Please double-space all your text. Use 1” margins all round. Use 12 pt font. The minimum number of pages should not be below 6 pages and maximum length should not exceed 8 pages (references not included).
A minimum of 8 primary literature citations should be used for the paper. Articles must be cited by author(s) and year within your text. For example, if there is a single author, the last name and year will suffice – e.g. (Hutchinson, 1995). If there are two authors, include both names and the year of the publication – e.g. (Hutchinson and Osborne, 1978). For more than two authors, use the first author with et al. – e.g. (Hutchinson et al., 1984). Include the list of references at the end of your paper. Do not include references you have read but not cited. List the references alphabetically by the first author’s last name followed by initials for first and middle name. All authors should be named in the citation. If there are more than five, list the first five author’s name followed by et al. Include the year published in parenthesis, followed by the full title for each cited article. Use MEDLINE/PubMed abbreviations of journal titles or use the full journal title for any journals not indexed in MEDLINE. Provide volume and issues for journal articles as applicable. Provide DOI numbers if volume/issue numbers are not available. Provide inclusive page ranges for journal articles and book chapters. Provide date of access for online sources. The only online resources that can be used is NIH.gov, CDC.gov and FDA.gov, Cite databases in the text.
• Journal articles should be cited as follows: Neuhaus J-M, Sitcher L, Meins F, Jr, Boller T (1991) A short C-terminal sequence is necessary and sufficient for the targeting of chitinases to the plant vacuole. Proc Natl Acad Sci USA 88(22):10362-10366.
• Articles or chapters in books are cited as follows: Hill AVS (1991) HLA associations with malaria in Africa: some implications for MHC evolution. Molecular Evolution of the Major Histocompatibility Complex, eds Klein J, Klein D (Springer, Heidelberg), pp 403-420.
Microorganisms must be named using binomial nomenclature, with the exception of viruses. Binomial nomenclature employs the names of the two lower level taxa, genus and species. Conventions when using binomial nomenclature include: genus comes before species and is always capitalized. Species name is never capitalized. Both names are always italicized. For example, Escherichia coli. If the name appears in several places in throughout the text you can abbreviate the genus name after it has been written in full length for the first time. For example, the abbreviation of Escherichia coli is E. coli. When specifying a particular strain, the genus name comes first, species name is second and strain name is last, followed by the serovar. The prefix subsp. is generally used to signify the strain. Everything should be italicized except the prefix subsp. and the serovar – Salmonella enterica subsp. enterica serovar Dublin. If the species is not fully identified, than the abbreviation “sp.” in the singular or “spp.” in the plural is used (e.g., Salmonella spp.). In this case, the name of the genus is written in italic, and sp. and spp. are written in normal font.
If figures are included, number them consecutively and give each a caption, as well as refer to them in your text by their number. Make sure that you include all the information necessary to interpret your figures. If figures are taken from other works, make sure you cite their original source.
• The term paper is due the last day of class, on the day of the final exam.
Final Paper Rubric
Grading Criteria
Formatting (25 points)
Is the main body broken down into sub-headings?
Research (20 points)
Does the outline reflect sufficient and appropriate knowledge of the project topic?
Scope (20 points)
Is it comprehensive coverage of the topic – long enough to meet page length requirement?
Content (20 points) Does it address all questions in the prompt?
Citations (15 points)
Does it cite at least three peer reviewed research or review publications?

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