Biomedical Engineering

Examine the structure using MolProbity and discuss its quality in terms of atom clashes, bond & angle geometry, side-chain

Examine the structure using MolProbity and discuss its quality in terms of atom clashes, bond & angle geometry, side-chain rotamers, backbone Ramachandran values, RNA sugar pucker and RNA backbone conformation. Is the MolProbity score “good” compared the resolution of the experiment? Attached is the MolProbity output Answer with a few paragraphs 🙂

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Date: September 8th, 2022

using your structure, write a PyMol script to display a) protein secondary structure hydrogen bonding and 2) polar contacts between the protein and DNA. You will need to use the “select” and “distance” commands. What types of secondary structure does your protein exhibit?

using your structure, write a PyMol script to display a) protein secondary structure hydrogen bonding and 2) polar contacts between the protein and DNA. You will need to use the “select” and “distance” commands. What types of secondary structure does your protein exhibit? Are there any protein side chains that may be in an incorrect […]

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Date: September 8th, 2022

A pharmaceutical company has decided to test the feasibility of manufacturing a new drug using biochemical engineering. In this approach, a valuable intermediate, intA, will be produced from raw materials using a genetically engineered bacterial strain

A pharmaceutical company has decided to test the feasibility of manufacturing a new drug using biochemical engineering. In this approach, a valuable intermediate, intA, will be produced from raw materials using a genetically engineered bacterial strain. After undergoing a series of chemical steps, this intermediate will then be converted to the final product. The following […]

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Date: August 5th, 2022