Posted: May 27th, 2022
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Please discuss the mechanisms that Bordetella pertussis, Streptococcus pneumoniae,
Corynebacterium diphtheriae and Mycobacterium tuberculosis utilize to cause disease in the
respiratory tract. You must state what disease these microorganisms cause and what role does
transduction play in their disease causing process. In addition, please discuss the host immune
defenses the microbes would have to overcome to be successful at causing disease. Also, please
discuss what the microbe could contain that would allow them to overcome these host immune
responses, and the association between normal flora and respiratory tract infections. Include a
discussion what roles personal hygiene, quorum sensing and sequential timing play in microbial
respiratory tract diseases. What’s a receptor-mediated process? What’s the significance of SOD
and catalase to the pathogenesis of Bordetella pertussis? What’s an obligate aerobe? What’s
generalized and specialized transduction and their significance to the pathogenesis of
Streptococcus pneumoniae and Corynebacterium diphtheriae?
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